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ESCO : Isolation Containment Streamline® Containment Isolator - Class III
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The Streamline® Containment Isolator Class III (SCI Class III) configuration solely operates in a negative pressure, with its on-board fan providing -37 Pa to -125 Pa (max) in the process chamber and -25 Pa to -75 Pa (max) in the pass-through chamber. "To comply fully with biosafety standards, the unit must be ducted to the building exhaust to meet negative pressure BSL-3 requirements." It provides an ISO Class 5 unidirectional total exhaust airflow, ensuring the sterility of the work zone during the whole manufacturing process. It is also equipped with double exhaust HEPA filters via Bag-In, Bag-Out (BIBO) system to prevent untoward exposure during filter change procedures. It has an option to place one (1) dunk at the side of the work zone (external). Plug and Play! For clients or facilities that do not have the capacity to provide a 100% ducting system, the SCI Class III and its optional feature for an integrated enhanced blower exhaust module system, can easily achieve a pressure of up to -125Pa.
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  • ULPA filters (as per IEST-RP-CC001.3 and HEPA (H14) filter as per EN 1822) with a typical efficiency of >99.999% at 0.1 to 0.3 microns, providing ISO Class 3 air cleanliness as per ISO 14644-1
  • FDA-grade pressure-tight static seals
  • Sentinel™ Gold microprocessor controller supervises all functions and monitors airflow and pressure in real-time
  • Robust dual-wall construction. Unique Esco Dynamic Chamber™ plenum surrounds filter seals with negative pressure
  • Safe-change cuff rings permit hypalon sleeve changes with zero risk of work zone or environment contamination


Principle

Total Exhaust

  • Ambient air is pulled through the inlet pre and main filter via the main fans at the top of the isolator. This creates positive pressure on the plenum which provides the downflow of air with a velocity of 0.40 m/s ± 20%.
    • The pre-filter extends the life of the filters by trapping larger particulates that can easily clog the main filters
  • This downflow supply then provides an ISO Class 5 environment and unidirectional airflow inside the isolator; thus, protecting the materials inside the main chamber and pass-through.
  • Air from the work zone and pass-through is then quickly purged by the fans to keep the area clean. The purge is completely exhausted through HEPA filters as well; ensuring that only clean air is exhausted back to the environment.